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Article

Insights into the structural characteristics and substrate binding analysis of chondroitin AC lyase (PsPL8A) from Pedobacter saltans.

International journal of biological macromolecules - 1 Apr 2018

Rani Aruna, Dhillon Arun, Sharma Kedar, Goyal Arun

Abstract excerpt

The structure of chondroitin AC lyase (PsPL8A) of family 8 polysaccharide lyase was characterized. Modeled PsPL8A structure showed, it contains N-terminal (α/α)6 incomplete toroidal fold and a layered β sandwich structure at C-terminal. Ramchandran plot displayed 98.5% residues in favoured and 1.2% in generously allowed region. Secondary structure of PsPL8A by CD revealed 27.31% α helices 22.7% β sheets and 49.9%...

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PMID: 29155196
DOI: 10.1016/j.ijbiomac.2017.11.087

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