Article
Identification and biochemical characterization of a novel chondroitin sulfate/dermantan sulfate lyase from Photobacterium sp.
International journal of biological macromolecules - 15 Dec 2020
Zhang Qingdong, Lu Danrong, Wang Shumin, Wei Lin, Wang Wenshuang, Li Fuchuan
Abstract excerpt
Chondroitin sulfate (CS)/dermatan sulfate (DS) lyases play important roles in structural and functional studies of CS/DS. In this study, a novel CS/DS lyase (enCSase) was identified from the genome of the marine bacterium Photobacterium sp. QA16. This enzyme is easily heterologously expressed and purified as highly active form against various CS, DS and hyaluronic acid (HA). Under the optimal conditions, the...
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