Article
Antigen levels of urokinase-type plasminogen activator receptor and its gene polymorphism related to microvessel density in colorectal cancer.
Acta biochimica Polonica - 1 Jan 2008
Przybylowska Karolina, Szemraj Janusz, Kulig Andrzej, Dziki Adam, Ulanska Joanna, Blasiak Janusz
Abstract excerpt
We determined the distribution of genotypes and frequencies of alleles of the (CA)(n) repeat polymorphism in intron 3 of the urokinase plasminogen activator receptor (uPAR) gene, uPAR antigen levels and microvessel density (MVD) in tumour and distant mucosa samples from 52 patients with colorectal cancer. The uPAR level was higher for patients with high MVD comparing to patients with lower MVD which may suggest...
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