Article
Urokinase receptor genotypes in colorectal cancer.
Carcinogenesis - 1 Jun 1998
Kohonen-Corish M, Young J, Chenevix-Trench G, Doe W F
Abstract excerpt
A previous study has reported a high frequency of rare alleles of the urokinase-type plasminogen activator receptor (uPAR) in a set of 15 colorectal cancer (CRC) cell lines. Our study investigated uPAR gene variation in 92 CRC patients and in tumour DNA from a subset of 69 patients using the PLAUR-IVS3 marker located in an intron of this gene. The overall distribution of the marker alleles in the patients did not...
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