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Article

A C/T polymorphism in the urokinase-type plasminogen activator gene in colorectal cancer.

Journal of experimental & clinical cancer research : CR - 1 Dec 2001

Przybylowska K, Smolarczyk K, Blasiak J, Kulig A, Romanowicz-Makowska H, Dziki A, Ulanska J, Pander B

Abstract excerpt

Urokinase plasminogen activation system can play an important role in the appearance and progression of many cancers. Urokinase-type plasminogen activator (uPA) is implicated in the control of cell adhesion and invasion, and is regarded as a strong prognostic marker in colorectal cancer. A C-->T substitution (the C/T polymorphism) in the nucleotide sequence encoding the kringle structure of uPA results in an...

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PMID: 11876553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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