Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the genes of the urokinase plasminogen activation system in relation to colorectal cancer.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Dec 2007

Försti A, Lei H, Tavelin B, Enquist K, Palmqvist R, Altieri A, Hallmans G, Hemminki K, Lenner P

Abstract excerpt

BACKGROUND: Extracellular matrix degradation, mediated by the urokinase plasminogen activation (uPA) system, is a critical step in tumor invasion and metastasis. High tumor levels of uPA and its inhibitor PAI-1 have been correlated with poor cancer prognosis. We examined four single nucleotide polymorphisms (SNPs) with a potential effect on expression of genes in the uPA system for their role in colorectal cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Survival Analysis

Share to Sweden

Share to Urokinase-Type Plasminogen Activator

Source

Identifiers

PMID: 17804466
DOI: 10.1093/annonc/mdm361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the genes of the urokinase plasminogen activation system in relation to colorectal cancer.PMID 17804466Read ↗

PAI-1 -675 4G/5G polymorphism as a prognostic biomarker in breast cancer.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 gene polymorphism and colorectal cancer risk and prognosis.Semantic proximity Read ↗

Evaluation of the association of urokinase plasminogen activator system gene polymorphisms with susceptibility and pathological development of hepatocellular carcinoma.Semantic proximity Read ↗

Association between Five Common Plasminogen Activator Inhibitor-1 (PAI-1) Gene Polymorphisms and Colorectal Cancer Susceptibility.Semantic proximity Read ↗

Clinicopathological significance of urokinase-type plasminogen activator genotypes in gastric cancer.Semantic proximity Read ↗

Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer.Semantic proximity Read ↗

A C/T polymorphism in the urokinase-type plasminogen activator gene in colorectal cancer.Semantic proximity Read ↗

Plasminogen activator inhibitor 1 (PAI-1) 1334G/A genetic polymorphism in colorectal cancer.Semantic proximity Read ↗

Urokinase receptor genotypes in colorectal cancer.Semantic proximity Read ↗

Clinical impact of PAI 1 4G/5G gene polymorphism in colorectal carcinoma patients.Semantic proximity Read ↗

Plasminogen activator inhibitor 1 (PAI-1) levels and gene promoter polymorphisms in subjects with colorectal cancer.Semantic proximity Read ↗

PAI-1 4G/5G polymorphism contributes to cancer susceptibility: evidence from meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.