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Article

Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM.

Frontiers in bioscience : a journal and virtual library - 1 May 2008

Munz Markus, Fellinger Karin, Hofmann Tanja, Schmitt Barbel, Gires Olivier

Abstract excerpt

Epithelial cell adhesion molecule EpCAM is strongly over-expressed in a variety of carcinomas where it is involved in signalling events resulting in increased expression of target genes such as c-Myc, cyclins and others, eventually conferring cells an oncogenic phenotype. However, EpCAM is also e...

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Identifiers

PMID: 18508581
DOI: 10.2741/3075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18508581-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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