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Article

EpCAM in carcinogenesis: the good, the bad or the ugly

13 Sept 2010

Abstract excerpt

The epithelial cell adhesion molecule (EpCAM) is a membrane glycoprotein that is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas. Interestingly, EpCAM is explored as target in antibody-based therapies. Recently, EpCAM has been identified as an additional marker of cancer-initiating cells. In this review, we describe the...

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PMID: 20837599
DOI: 10.1093/carcin/bgq187

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