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Article

PPARdelta increases expression of the human apolipoprotein A-II gene in human liver cells.

International journal of molecular medicine - 1 Jun 2008

Thulin Petra, Glinghammar Björn, Skogsberg Josefin, Lundell Kerstin, Ehrenborg Ewa

Abstract excerpt

The peroxisome proliferator-activated receptor delta (PPARdelta) is a transcription factor that regulates genes of importance in lipid and glucose metabolism. ApoA-II is one of the major proteins of the HDL-particle. The aim of this study was to investigate the regulation of apoA-II gene expression by PPARdelta. Treatment of HepG2 cells with the PPARdelta specific agonist GW501516 increased apoA-II mRNA...

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PMID: 18506377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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