Article
Alternative splicing of human peroxisome proliferator-activated receptor delta (PPAR delta): effects on translation efficiency and trans-activation ability.
BMC molecular biology - 16 Aug 2007
Lundell Kerstin, Thulin Petra, Hamsten Anders, Ehrenborg Ewa
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptor delta (PPAR delta) is a member of the nuclear receptor superfamily. Numerous studies have aimed at unravelling the physiological role of PPAR delta as a transcriptional regulator whereas the regulation of PPAR delta gene expression has been less studied. RESULTS: The principal transcription start site in the human PPAR delta gene identified here is positioned...
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