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Article

Characterization of the Human PPARα Promoter: Identification of a Functional Nuclear Receptor Response Element

1 May 2002

Abstract excerpt

PPARalpha is a nuclear receptor that controls lipid and glucose metabolism and exerts antiinflammatory activities. The factors regulating human PPARalpha (hPPARalpha) gene expression remain largely unexplored. To study the mechanisms controlling hPPARalpha expression, the hPPARalpha gene promoter was identified and characterized. First, an alternatively spliced exon within the 5'-untranslated region of the...

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PMID: 11981036
DOI: 10.1210/mend.16.5.0833

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