Article
PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function.
Current opinion in lipidology - 1 Aug 2009
Karpe Fredrik, Ehrenborg Ewa E
Abstract excerpt
PURPOSE OF REVIEW: Abundant data in rodents suggest an important role for peroxisomal proliferators-activated receptor-delta (PPARdelta) in regulating skeletal muscle fatty acid oxidation and this has consequences for lipid and lipoprotein metabolism. Considerably less is known in humans and this review will focus on evidence derived from studies of the PPARD gene and pharmacological use of specific PPARdelta...
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