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Article

Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis

27 Jan 2010

Abstract excerpt

The transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha) is an important regulator of hepatic lipid metabolism. While PPARalpha is known to activate transcription of numerous genes, no comprehensive picture of PPARalpha binding to endogenous genes has yet been reported. To fill this gap, we performed Chromatin immunoprecipitation (ChIP)-chip in combination with transcriptional...

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PMID: 20110263
DOI: 10.1093/nar/gkq012

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