Article
Impact of genetic variation of PPARgamma in humans.
Molecular genetics and metabolism - 1 Jan 2000
Meirhaeghe Aline, Amouyel Philippe
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a transcription factor with a key role in adipocyte differentiation. Since 1997, studies of rare mutations and common polymorphisms of the PPARgamma gene have enabled us to expand our knowledge of the role of this transcription factor in humans. Rare monogenic mutations in PPARgamma have a limited impact on the health of the population due to their...
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