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Article

Coordinate regulation of bovine prion protein gene promoter activity by two Sp1 binding site polymorphisms.

Biochemical and biophysical research communications - 8 Aug 2008

Xue Guangai, Sakudo Akikazu, Kim Chi-kyeong, Onodera Takashi

Abstract excerpt

Relationships between insertion/deletion (Ins/Del) polymorphisms of the bovine prion protein gene (PRNP) promoter and bovine spongiform encephalopathy (BSE) susceptibility have been reported. Our previous study has shown that polymorphisms of -6C-->T included in the specific protein 1 (Sp1) site in the 5'-flanking region of bovine PRNP influence the promoter activity of bovine PRNP. The present study shows that...

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Identifiers

PMID: 18505676
DOI: 10.1016/j.bbrc.2008.05.085

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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