Article
Detection of bovine spongiform encephalopathy-related prion protein gene promoter polymorphisms in local Turkish cattle.
Biochemical genetics - 1 Dec 2008
Un Cemal, Oztabak Kemal, Ozdemir Nehir, Tesfaye Dawit, Mengi Ahmet, Schellander Karl
Abstract excerpt
Polymorphisms in open reading frames of the prion protein gene (PRNP) have been shown to be associated with prion disease susceptibility in humans, sheep, and mice. Studies in recent years have demonstrated a similar effect of PRNP promoter and intron-1 polymorphisms on bovine spongiform encephalopathy (BSE) susceptibility in cattle. In this study, the deletion/insertion (indel) polymorphisms of the bovine PRNP...
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