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Article

Novel single nucleotide polymorphisms in the specific protein 1 binding site of the bovine PRNP promoter in Japanese Black cattle: impairment of its promoter activity.

Intervirology - 1 Jan 2007

Nakamura Izuru, Xue Guangai, Sakudo Akikazu, Saeki Keiichi, Matsumoto Yoshitsugu, Ikuta Kazuyoshi, Onodera Takashi

Abstract excerpt

Susceptibility to transmissible spongiform encephalopathy and different alleles of the prion protein gene (PRNP) of humans and sheep are associated. A tentative association between PRNP promoter polymorphisms and bovine spongiform encephalopathy (BSE) susceptibility has been reported in German cattle, whereas none of the known polymorphisms within the bovine PRNP-coding sequence affect BSE susceptibility. In the...

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Identifiers

PMID: 17283444
DOI: 10.1159/000099217

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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