Article
Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon.
Biochemical and biophysical research communications - 1 Aug 2008
Fukunaga Ryuya, Harada Yoko, Hirao Ichiro, Yokoyama Shigeyuki
Abstract excerpt
An unnatural base pair between 7-(2-thienyl)-imidazo[4,5-b]pyridine (Ds) and pyrrole-2-carbaldehyde (Pa) could expand the genetic alphabet and allow the incorporation of non-standard amino acids into proteins at defined positions. For this purpose, we synthesized tRNAs bearing Pa at the anticodon...
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