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Article

Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipients.

Steroids - 1 Oct 2008

Miura Masatomo, Satoh Shigeru, Inoue Kazuyuki, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Habuchi Tomonori, Suzuki Toshio

Abstract excerpt

The objective of this study was to evaluate whether genetic polymorphisms of CYP3A5 (A6986G, CYP3A5*3), ABCB1 (C1236T, G2677T/A, C3435T) and NR1I2 (A7635G) significantly impact the pharmacokinetics of prednisolone in renal transplant recipients. Ninety-five recipients were given repeated doses of triple therapy immunosuppression consisting of prednisolone, tacrolimus and mycophenolate mofetil. Twenty-eight days...

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Source

Identifiers

PMID: 18502461
DOI: 10.1016/j.steroids.2008.04.002

Genes

ABCB1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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