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Article

Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A53/3.

Biochemical genetics - 1 Jun 2017

Ito Ayano, Okada Yuko, Hashita Tadahiro, Aomori Tohru, Hiromura Keiju, Nojima Yoshihisa, Nakamura Tomonori, Araki Takuya, Yamamoto Koujirou

Abstract excerpt

The purpose of this study was to describe the impact of sex and cytochrome P450 3A5 (CYP3A5) variant on the blood concentration of tacrolimus in patients with systemic lupus erythematosus or rheumatoid arthritis. The blood concentration of tacrolimus (ng/mL) divided by the daily dose of tacrolimus (mg/day) and the patient's weight (kg) (C/D) was obtained from 55 patients. The C/D value was analysed according to...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to Lupus Erythematosus, Systemic

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Source

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Identifiers

PMID: 28324194
DOI: 10.1007/s10528-017-9795-8
PMCID: PMC5438821

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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