Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenetics of immunosuppressants: progress, pitfalls and promises.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Jul 2008

Cattaneo D, Baldelli S, Perico N

Abstract excerpt

Most of the immunosuppressants used in organ transplantation are characterized by a narrow therapeutic index, whereby underdosing is associated with increased risk of rejection episodes and overdosing may exacerbate drug-related toxicity. Pharmacogenetics--complementary to pharmacokinetics--holds the potential to allow individualized dosing of immunosuppressive agents to optimize their therapeutic actions while...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cytochrome P-450 CYP3A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Rejection

Share to Immunosuppressive Agents

Share to Methyltransferases

Share to Organ Transplantation

Share to Pharmacogenetics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18510642
DOI: 10.1111/j.1600-6143.2008.02263.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetics of immunosuppressants: progress, pitfalls and promises.PMID 18510642Read ↗

Pharmacogenetics in solid organ transplantation: current status and future directions.Semantic proximity Read ↗

Pharmacogenetics in solid organ transplantation: present knowledge and future perspectives.Semantic proximity Read ↗

Practicability of pharmacogenetics in transplantation medicine.Semantic proximity Read ↗

Role of Pharmacogenetics of Immunosuppressive Drugs in Organ TransplantationSemantic proximity Read ↗

Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapySemantic proximity Read ↗

Biotransformation enzymes and drug transporters pharmacogenetics in relation to immunosuppressive drugs: impact on pharmacokinetics and clinical outcome.Semantic proximity Read ↗

Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted PatientsSemantic proximity Read ↗

Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update.Semantic proximity Read ↗

CYP3A polymorphisms and immunosuppressive drugs in solid-organ transplantation.Semantic proximity Read ↗

Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations.Semantic proximity Read ↗

Trends in Precision Medicine and Pharmacogenetics as an Adjuvant in Establishing a Correct Immunosuppressive Therapy for Kidney Transplant: An Up-to-Date Historical OverviewSemantic proximity Read ↗

Genetic factors for individual administration of immunosuppressants in organ transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.