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Article

NR1I2 polymorphisms are related to tacrolimus dose-adjusted exposure and BK viremia in adult kidney transplantation.

Transplantation - 27 Nov 2012

Barraclough Katherine A, Isbel Nicole M, Lee Katie J, Bergmann Troels K, Johnson David W, McWhinney Brett C, Ungerer Jacobus P J, Campbell Scott B, Leary Diana R, Bialasiewicz Seweryn, Rockett Rebecca J, Staatz Christine E

Abstract excerpt

BACKGROUND: Pregnane X, encoded by the gene NR112, is a nuclear receptor whose primary role is to promote the detoxification and clearance of drugs and other foreign compounds from the body. AIM: The aim of this study was to analyze associations between NR1I2 polymorphisms, immunosuppressant drug exposure, and clinical outcomes in adult kidney transplant recipients. METHODS: Exposures to tacrolimus, mycophenolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23095803
DOI: 10.1097/TP.0b013e31826c3985

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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