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Article

The 5'-terminal nucleotides of hepatitis A virus RNA, but not poliovirus RNA, are required for infectivity.

Journal of virology - 1 May 1991

Harmon S A, Richards O C, Summers D F, Ehrenfeld E

Abstract excerpt

A series of plasmids containing hepatitis A virus (HAV) cDNA was constructed such that positive-strand HAV RNA could be transcribed with T7 RNA polymerase. The plasmids differed in the number of 5'-terminal nucleotides representing the junctions between vectors and HAV sequences that were present in the transcripts. When these transcripts were used to transfect cultured BS-C-1 cells, it was found that only those...

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Identifiers

PMID: 1850050
DOI: 10.1128/JVI.65.5.2757-2760.1991
PMCID: PMC240644

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