Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immortalization of mouse intestinal epithelial cells by the SV40-large T gene. Phenotypic and immune characterization of the MODE-K cell line.

Journal of immunological methods - 5 Nov 1993

Vidal K, Grosjean I, evillard J P, Gespach C, Kaiserlian D

Abstract excerpt

Intestinal epithelial cells from the mouse small intestine were immortalized by SV40 large T gene transfer through a murine ecotropic virus. The resulting cell lines expressed the SV40 large T mRNA and exhibited morphological and phenotypic characteristics of normal enterocytes, including intercellular junctions, and expression of cytokeratin, villin, poly-Ig receptor (i.e., secretory component) and vasoactive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Histocompatibility Antigens Class II

Share to Microscopy, Electron

Share to Phenotype

Share to RNA, Messenger

Source

Identifiers

PMID: 7693823
DOI: 10.1016/0022-1759(93)90329-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immortalization of mouse intestinal epithelial cells by the SV40-large T gene. Phenotypic and immune characterization of the MODE-K cell line.PMID 7693823Read ↗

Transimmortalized mouse intestinal cells (m-ICc12) that maintain a crypt phenotype.Semantic proximity Read ↗

Cytolytic and IFN-gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are T cell receptor-beta-chain dependent.Semantic proximity Read ↗

Immortalization of epithelial cells.Semantic proximity Read ↗

Failure of T cell receptor V beta negative selection in murine intestinal intra-epithelial lymphocytes.Semantic proximity Read ↗

Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirusSemantic proximity Read ↗

Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro.Semantic proximity Read ↗

Phenotype and TCR gamma delta variable gene repertoire of intestinal intraepithelial lymphocytes in wild mice (Mus musculus domesticus): abundance of V gamma 1 transcripts and extensive delta gene diversity.Semantic proximity Read ↗

Establishment of mouse intestinal myofibroblast cell lines.Semantic proximity Read ↗

Intestinal Intraepithelial Lymphocyte γδ-T Cell-Derived Keratinocyte Growth Factor Modulates Epithelial Growth in the MouseSemantic proximity Read ↗

Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes.Semantic proximity Read ↗

Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40.Semantic proximity Read ↗

Cell culture modeling of specialized tissue: identification of genes expressed specifically by follicle-associated epithelium of Peyer's patch by expression profiling of Caco-2/Raji co-culturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.