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Article

Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40.

Cellular immunology - 1 Dec 1991

Watt S M, Thomas J A, Murdoch S J, Kearney L, Chang S E, Bartek J

Abstract excerpt

The thymic microenvironment contains a mixture of phenotypically distinct epithelial cells of varied functions, some of which are unknown. In an attempt to understand their relevance to T cell differentiation in the thymus, human thymic epithelial cell clones from both fetal (SM3-SM5) and postnatal (SM6) thymus were produced by using a defective recombinant retroviral vector encoding the simian virus 40 large T...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1718608
DOI: 10.1016/0008-8749(91)90169-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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