Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40.

doi:10.1016/0008-8749(91)90169-c

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Article

Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40.

Cellular immunology - 1 Dec 1991

Watt S M, Thomas J A, Murdoch S J, Kearney L, Chang S E, Bartek J

Abstract excerpt

The thymic microenvironment contains a mixture of phenotypically distinct epithelial cells of varied functions, some of which are unknown. In an attempt to understand their relevance to T cell differentiation in the thymus, human thymic epithelial cell clones from both fetal (SM3-SM5) and postnat...

Topics

Cell Division
Cell Transformation, Viral
Cells, Cultured
Clone Cells
Epithelium
Female
Genetic Vectors
Humans
Keratins
Phenotype
Pregnancy
Simian virus 40
Thymus Gland

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