Article
Biomolecular detection with a thin membrane transducer.
Lab on a chip - 1 Jun 2008
Cha Misun, Shin Jaeha, Kim June-Hyung, Kim Ilchaek, Choi Junbo, Lee Nahum, Kim Byung-Gee, Lee Junghoon
Abstract excerpt
We present a thin membrane transducer (TMT) that can detect nucleic acid based biomolecular reactions including DNA hybridization and protein recognition by aptamers. Specific molecular interactions on an extremely thin and flexible membrane surface cause the deflection of the membrane due to surface stress change which can be measured by a compact capacitive circuit. A gold-coated thin PDMS membrane assembled...
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