Article
DNA detection using a triple readout optical/AFM/MALDI planar microwell plastic chip.
Analytical chemistry - 1 Aug 2008
Ibáñez Alfredo J, Schüler Thomas, Möller Robert, Fritzsche Wolfgang, Saluz Hans-Peter, Svatos Ales
Abstract excerpt
A ready-to-spot disposable DNA chip for specific and sensitive detection of DNA was developed. Plastic copolymeric substrate chemistry was optimized to selectively couple the target DNA with the active chip surface. At the same time, the developed substrate limits the unspecific adsorption of probe DNA molecules or additional polar contaminants in the test samples to the chip surface. The combination of glycidyl...
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