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Article

A cystic fibrosis bronchial epithelial cell line: immortalization by adeno-12-SV40 infection.

American journal of respiratory cell and molecular biology - 1 Apr 1991

Zeitlin P L, Lu L, Rhim J, Cutting G, Stetten G, Kieffer K A, Craig R, Guggino W B

Abstract excerpt

An immortalized cell line was created from a primary culture of bronchial epithelia isolated from a patient with cystic fibrosis. The culture was transformed with a hybrid virus, adeno-12-SV40, which has been used successfully on a number of different human epithelial tissues. The transformed bronchial epithelial cells have the following characteristics. (1) Cyclic adenosine monophosphate (cAMP) is stimulated by...

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Source

Identifiers

PMID: 1849726
DOI: 10.1165/ajrcmb/4.4.313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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