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Article

Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype.

The American journal of physiology - 1 May 1993

Yankaskas J R, Haizlip J E, Conrad M, Koval D, Lazarowski E, Paradiso A M, Rinehart C A, Sarkadi B, Schlegel R, Boucher R C

Abstract excerpt

Human airway epithelial cell lines that retain phenotypic properties representative of the native tissue will be useful physiological models. Human papilloma viral (HPV) genes can immortalize human genital keratinocytes and breast and bronchial epithelia. We transfected cystic fibrosis (CF) and normal tracheobronchial epithelial cell cultures with DNA encoding the HPV-18 E6 and E7 genes and characterized...

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Source

Identifiers

PMID: 7684560
DOI: 10.1152/ajpcell.1993.264.5.C1219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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