Article
Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype.
The American journal of physiology - 1 May 1993
Yankaskas J R, Haizlip J E, Conrad M, Koval D, Lazarowski E, Paradiso A M, Rinehart C A, Sarkadi B, Schlegel R, Boucher R C
Abstract excerpt
Human airway epithelial cell lines that retain phenotypic properties representative of the native tissue will be useful physiological models. Human papilloma viral (HPV) genes can immortalize human genital keratinocytes and breast and bronchial epithelia. We transfected cystic fibrosis (CF) and n...
Topics
- Adult
- Animals
- Bradykinin
- Calcium
- Carbachol
- Cell Differentiation
- Cell Division
- Cell Line, Transformed
- Cell Membrane
- Cells, Cultured
- Chloride Channels
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA-Binding Proteins
- Epithelium