Article
Differentiation of immortalized epithelial cells derived from cystic fibrosis airway submucosal glands.
In vitro cellular & developmental biology. Animal - 1 Aug 1994
Chopra D P, Reddy L, Gupta S K, Wan L, Mathieu P A, Shoemaker R L, Rhim J S
Abstract excerpt
Cystic fibrosis (CF) involves abnormalities in mucus production and secretion of the airway. Studies of the regulation of airway mucin production and secretion has been difficult due to the lack of in vitro models of the airway epithelial cells which express functional differentiation. Because the majority of the mucin in the airway is apparently produced by the submucosal glands, we have focused our attention on...
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