Article
Transforming growth factor-beta1 and major depressive disorder with and without attempted suicide: preliminary study.
Psychiatry research - 30 Jun 2010
Lee Hwa-Young, Kim Yong-Ku
Abstract excerpt
A substantial body of evidence indicates that dysregulation of the immune system is associated with suicidal behavior in major depressive disorder (MDD). Transforming growth factor (TGF)-beta1 is believed to be an important factor in regulating inflammatory responses and to have anti-inflammatory effects. We aimed to identify the role of TGF-beta1 on suicidal depression. The TGF-beta1 polymorphisms at codons 10...
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