Article
TNF-alpha -308G>A polymorphism is associated with suicide attempts in major depressive disorder.
Journal of affective disorders - 5 Sept 2013
Kim Yong-Ku, Hong Jin-Pyo, Hwang Jung-A, Lee Heon-Jeong, Yoon Ho-Kyoung, Lee Bun-Hee, Jung Han-Yong, Hahn Sang-Woo, Na Kyoung-Sae
Abstract excerpt
BACKGROUND: Despite the substantial role of the cytokine network in depression and suicide, few studies have investigated the role of genetic polymorphisms of pro- and anti-inflammatory cytokines in suicide in major depressive disorder (MDD). The aim of this study was to investigate whether tumor necrosis factor-alpha (TNF-alpha) -308G>A, interferon-gamma (IFN-gamma) +874A>T, and interleukin-10 (IL-10) -1082A>G...
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