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Article

Role of serotonergic-related systems in suicidal behavior: Data from a case-control association study.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2011

Saiz Pilar A, García-Portilla Paz, Paredes Begoña, Corcoran Paul, Arango Celso, Morales Blanca, Sotomayor Emilio, Alvarez Victoria, Coto Eliecer, Flórez Gerardo, Bascaran María-Teresa, Bousoño Manuel, Bobes Julio

Abstract excerpt

OBJECTIVE: To investigate whether functional polymorphisms directly (HTR2A and SLC6A4 genes) or indirectly (IL-1 gene complex, APOE and ACE genes) related with serotonergic neurotransmission were associated with suicidal behavior. SUBJECTS AND METHODS: 227 suicide attempters, 686 non-suicidal psychiatric patients, and 420 healthy controls from a homogeneous Spanish Caucasian population were genotyped using...

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Identifiers

PMID: 21575667
DOI: 10.1016/j.pnpbp.2011.04.011

Genes

APOE
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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