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Article

Cumulative effect of five genetic variants on prostate cancer risk in multiple study populations.

The Prostate - 1 Sept 2008

Sun Jielin, Chang Bao-Li, Isaacs Sarah D, Wiley Kathleen E, Wiklund Fredrik, Stattin Pär, Duggan David, Carpten John D, Trock Bruce J, Partin Alan W, Walsh Patrick C, Grönberg Henrik, Xu Jianfeng, Isaacs William B, Zheng S Lilly

Abstract excerpt

BACKGROUND: A strong cumulative effect of five genetic variants and family history on prostate cancer risk was recently reported in a Swedish population (CAPS). We carried out this study to confirm the finding in two U.S. study populations and perform a combined analysis to obtain a more stable estimate of the odds ratio (OR) for prostate cancer. METHODS: We evaluated three SNPs at 8q24 and one SNP each at 17q12...

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Identifiers

PMID: 18491292
DOI: 10.1002/pros.20793
PMCID: PMC2800258

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CAPS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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