Article
Genome-wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families.
The Prostate - 1 Dec 2003
Xu Jianfeng, Gillanders Elizabeth M, Isaacs Sarah D, Chang Bao-Li, Wiley Kathy E, Zheng S Lilly, Jones MaryPat, Gildea Derek, Riedesel Erica, Albertus Julie, Freas-Lutz Diana, Markey Carol, Meyers Deborah A, Walsh Patrick C, Trent Jeffrey M, Isaacs William B
Abstract excerpt
BACKGROUND: Although the subject of intensive study, the genetic influences responsible for familial clustering of prostate cancer remain largely unidentified. Genome-wide scans for linkage in prostate cancer families can be used to systematically search for genes capable of affecting risk for the disease. METHODS: All available family members from 188 families, each having at least three first-degree relatives...
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