Article
Cumulative association of five genetic variants with prostate cancer.
The New England journal of medicine - 28 Feb 2008
Zheng S Lilly, Sun Jielin, Wiklund Fredrik, Smith Shelly, Stattin Pär, Li Ge, Adami Hans-Olov, Hsu Fang-Chi, Zhu Yi, Bälter Katarina, Kader A Karim, Turner Aubrey R, Liu Wennuan, Bleecker Eugene R, Meyers Deborah A, Duggan David, Carpten John D, Chang Bao-Li, Isaacs William B, Xu Jianfeng, Grönberg Henrik
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in five chromosomal regions--three at 8q24 and one each at 17q12 and 17q24.3--have been associated with prostate cancer. Each SNP has only a moderate association, but when SNPs are combined, the association may be stronger. METHODS: We evaluated...
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