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Article

GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development.

Investigative ophthalmology & visual science - 1 Oct 2008

Jin Chang, Yin Furong, Lin Mimi, Li Hongxia, Wang Zhenlian, Weng Jinsheng, Liu Mingyao, Da Dong Xiang, Qu Jia, Tu LiLi

Abstract excerpt

PURPOSE: Eyelid development is a dynamic process involving cell proliferation, differentiation, and migration regulated by a number of growth factors and cytokines. Mice deficient in the orphan G protein-coupled receptor 48 (GPR48) showed an eye open at birth (EOB) phenotype. In this study, the a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Nick-End Labeling

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Share to Microscopy, Electron, Scanning

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 18487371
DOI: 10.1167/iovs.08-1860

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18487371-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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