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GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing

21 Jan 2015

Abstract excerpt

G protein-coupled receptors (GPCRs) mediate multiple key biological processes in the body. The orphan receptor GPR39 has been reported to be involved in various pathophysiological events. However, the function of GPR39 in skin biology remains unknown. Using a genetically engineered mouse strain in which lacZ expression faithfully replaced endogenous Gpr39 expression, we discovered a unique expression pattern of...

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PMID: 25604641
DOI: 10.1038/srep07913

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