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Article

Platelet reactivity and clopidogrel resistance are associated with the H2 haplotype of the P2Y12-ADP receptor gene.

International journal of cardiology - 17 Apr 2009

Staritz Peter, Kurz Kerstin, Stoll Monika, Giannitsis Evangelos, Katus Hugo A, Ivandic Boris T

Abstract excerpt

BACKGROUND: Platelet hyperreactivity was reported in clopidogrel-naiotave carriers of the H2 haplotype of the P2Y(12) platelet ADP receptor. Here, we studied the influence of this genetic variant on clopidogrel responsiveness. METHODS: ADP-mediated (5 micromol/L) platelet aggregation was determined by impedance (Omega) aggregometry in 43 clopidogrel-naïve blood donors and 557 patients treated with aspirin and...

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Source

Identifiers

PMID: 18485500
DOI: 10.1016/j.ijcard.2007.12.118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Platelet reactivity and clopidogrel resistance are associated with the H2 haplotype of the P2Y12-ADP receptor gene.PMID 18485500Read ↗

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