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Article

LKB1 and Lung Cancer: More Than the Usual Suspects

15 May 2008

Abstract excerpt

Often, the problem in cancer research is figuring out how a gene or pathway works in regulating cellular transformation. The question of what RAS activates or PTEN inhibits have been classic dilemmas of modern cancer biology. In these cases, biochemical and genetic studies have provided us with a fairly clear picture of the cancer relevant functions of these genes. For LKB1, a more recently identified human tumor...

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PMID: 18483235
DOI: 10.1158/0008-5472.can-07-6620

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