Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site.

Journal of virology - 1 Apr 1991

Prince V E, Rigby P W

Abstract excerpt

The long terminal repeat (LTR) sequences of Moloney murine leukemia virus and its closely related derivative Moloney murine sarcoma virus (Mo-MSV) are incapable of directing transcription in embryonal carcinoma (EC) stem cells. The myeloproliferative sarcoma virus, a derivative of Mo-MSV, has several point mutations in the LTR and is transcribed more efficiently to allow productive infection of F9 EC cells. One...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Binding Sites
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Molecular Sequence Data

Share to Mutation

Share to Repetitive Sequences, Nucleic Acid

Share to RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 1848307
DOI: 10.1128/JVI.65.4.1803-1811.1991
PMCID: PMC239988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site.PMID 1848307Read ↗

A single point mutation activates the Moloney murine leukemia virus long terminal repeat in embryonal stem cells.Semantic proximity Read ↗

Induction of Sp1-p53 DNA-binding heterocomplexes during granulocyte/macrophage colony-stimulating factor-dependent proliferation in human erythroleukemia cell line TF-1.Semantic proximity Read ↗

In vivo analysis of retroviral enhancer mutations in hematopoietic cells: SP1/EGR1 and ETS/GATA motifs contribute to long terminal repeat specificity.Semantic proximity Read ↗

Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells.Semantic proximity Read ↗

Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.Semantic proximity Read ↗

Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.Semantic proximity Read ↗

Replication of a Moloney murine leukemia virus mutant lacking the ELP binding site.Semantic proximity Read ↗

c-ets-1 DNA binding to the PEA3 motif is differentially inhibited by all the mutations found in v-ets.Semantic proximity Read ↗

Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1.Semantic proximity Read ↗

Two Sp1/Sp3 Binding Sites in the Major Immediate-Early Proximal Enhancer of Human Cytomegalovirus Have a Significant Role in Viral ReplicationSemantic proximity Read ↗

Activation of cryptic splice sites in murine sarcoma virus-124 mutants.Semantic proximity Read ↗

Reversion of thermosensitive splicing defect of Moloney murine sarcoma virus ts110 by oversplicing of viral RNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.