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Article

In vivo analysis of retroviral enhancer mutations in hematopoietic cells: SP1/EGR1 and ETS/GATA motifs contribute to long terminal repeat specificity.

Journal of virology - 1 Jan 2002

Wahlers Anke, Zipfel Peter F, Schwieger Maike, Ostertag Wolfram, Baum Christopher

Abstract excerpt

The objective of this work was to identify, in the context of chromosomally integrated DNA, the contribution of defined transcription factor binding motifs to the function of a complex retrovirus enhancer in hematopoietic cells in vivo. Repopulating murine hematopoietic cells were transduced with equal gene dosages of replication-incompetent retrovirus vectors encoding enhanced green fluorescent protein. Enhancer...

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Share to Enhancer Elements, Genetic
Share to Erythroid-Specific DNA-Binding Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GATA1 Transcription Factor

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Share to Mice, Inbred C57BL

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Source

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Identifiers

PMID: 11739695
DOI: 10.1128/jvi.76.1.303-312.2002
PMCID: PMC135690

Genes

EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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