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Article

Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.

Journal of leukocyte biology - 1 Oct 2013

Yanaba Koichi, Kamata Masahiro, Ishiura Nobuko, Shibata Sayaka, Asano Yoshihide, Tada Yayoi, Sugaya Makoto, Kadono Takafumi, Tedder Thomas F, Sato Shinichi

Abstract excerpt

Psoriasis is an inflammatory cutaneous disorder characterized by marked epidermal thickening and Th1 and Th17 cell infiltration. At present, the contribution of B cells to the pathogenesis of psoriasis is unclear. In mice, topical application of imiquimod induces inflamed skin lesions and serves as an experimental animal model for human psoriasis. In this study, we showed that imiquimod-induced skin inflammation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23630391
DOI: 10.1189/jlb.1112562
PMCID: PMC3774845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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