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Peptide concentrations and mRNA expression of IGF-I, IGF-II and IGFBP-3 in breast cancer and their associations with disease characteristics.

Breast cancer research and treatment - 1 May 2009

Mu Lina, Katsaros Dionyssios, Wiley Andrew, Lu Lingeng, de la Longrais Irene A Rigault, Smith Stephanie, Khubchandani Sapna, Sochirca Olga, Arisio Riccardo, Yu Herbert

Abstract excerpt

PURPOSE: To measure peptide concentrations and mRNA expression of the IGF Family in breast cancer and to examine their associations with the disease features. EXPERIMENTAL DESIGN: Fresh tumor samples were collected from 348 patients who underwent surgery for breast cancer. Tissue levels of mRNA and peptide of IGF-I, IGF-II, and IGFBP-3 were analyzed with real-time RT-PCR and ELISA, respectively. Cox proportional...

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PMID: 18481170
DOI: 10.1007/s10549-008-0046-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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