Article
Insulin-like growth factor (IGF)-system mRNA quantities in normal and tumor breast tissue of women with sporadic and familial breast cancer risk.
Breast cancer research and treatment - 1 Apr 2004
Voskuil Dorien W, Bosma Astrid, Vrieling Alina, Rookus Matti A, van 't Veer Laura J
Abstract excerpt
The insulin-like growth factor (IGF)-system plays a role in breast cancer susceptibility as well as in growth and progression of breast carcinomas. So far, findings have been based on serum IGF-I levels and semi-quantitative assessment of IGF-system expression levels in model systems and human tissue. Quantitative data on mRNA expression in different types of human breast tissue are lacking. Breast tissue samples...
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