Article
Protein phosphatase type 1 directs chitin synthesis at the bud neck in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Jul 2008
Larson Jennifer R, Bharucha Jennifer P, Ceaser Shantelle, Salamon Joanna, Richardson Charles J, Rivera Segalit M, Tatchell Kelly
Abstract excerpt
Yeast chitin synthase III (CSIII) is targeted to the bud neck, where it is thought to be tethered by the septin-associated protein Bni4. Bni4 also associates with the yeast protein phosphatase (PP1) catalytic subunit, Glc7. To identify regions of Bni4 necessary for its targeting functions, we created a collection of 23 deletion mutants throughout the length of Bni4. Among the deletion variants that retain the...
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