Article
Septin ring assembly requires concerted action of polarisome components, a PAK kinase Cla4p, and the actin cytoskeleton in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Dec 2004
Kadota Jun, Yamamoto Takaharu, Yoshiuchi Shiro, Bi Erfei, Tanaka Kazuma
Abstract excerpt
Septins are filament-forming proteins that function in cytokinesis in a wide variety of organisms. In budding yeast, the small GTPase Cdc42p triggers the recruitment of septins to the incipient budding site and the assembly of septins into a ring. We herein report that Bni1p and Cla4p, effectors of Cdc42p, are required for the assembly of the septin ring during the initiation of budding but not for its...
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