Article
The Saccharomyces cerevisiae actin cytoskeletal component Bsp1p has an auxiliary role in actomyosin ring function and in the maintenance of bud-neck structure.
Genetics - 1 Apr 2008
Wright Daniel J, Munro Ewen, Corbett Mark, Bentley Adam J, Fullwood Nigel J, Murray Stephen, Price Clive
Abstract excerpt
Iqg1p is a component of the actomyosin contractile ring that is required for actin recruitment and septum deposition. Cells lacking Iqg1p function have an altered bud-neck structure and fail to form a functional actomyosin contractile ring resulting in a block to cytokinesis and septation. Here it is demonstrated that increased expression of the actin cytoskeleton associated protein Bsp1p bypasses the requirement...
Topics
- Actins
- Actomyosin
- Adaptor Proteins, Vesicular Transport
- Cell Wall
- Chitin
- Chitin Synthase
- Cytoskeleton
- Fluorescence Resonance Energy Transfer
- Fungal Proteins
- MAP Kinase Signaling System
- Mutation
- Phenotype
- Protein Binding