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Article

Septins, under Cla4p regulation, and the chitin ring are required for neck integrity in budding yeast.

Molecular biology of the cell - 1 May 2003

Schmidt Martin, Varma Archana, Drgon Tomás, Bowers Blair, Cabib Enrico

Abstract excerpt

CLA4, encoding a protein kinase of the PAK type, and CDC11, encoding a septin, were isolated in a screen for synthetic lethality with CHS3, which encodes the chitin synthase III catalytic moiety. Although Ste20p shares some essential function with Cla4p, it did not show synthetic lethality with Chs3p. cla4 and cdc11 mutants exhibited similar morphological and septin localization defects, including aberrant and...

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Identifiers

PMID: 12802080
DOI: 10.1091/mbc.e02-08-0547
PMCID: PMC165102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Septins, under Cla4p regulation, and the chitin ring are required for neck integrity in budding yeast.PMID 12802080Read ↗

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Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p.Semantic proximity Read ↗

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The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions.Semantic proximity Read ↗

Synthetic lethal analysis implicates Ste20p, a p21-activated potein kinase, in polarisome activation.Semantic proximity Read ↗

Interplay between septin organization, cell cycle and cell shape in yeast.Semantic proximity Read ↗

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Cyk3 acts in actomyosin ring independent cytokinesis by recruiting Inn1 to the yeast bud neckSemantic proximity Read ↗

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