Article
An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae.
BMC genetics - 16 Feb 2005
Lesage Guillaume, Shapiro Jesse, Specht Charles A, Sdicu Anne-Marie, Ménard Patrice, Hussein Shamiza, Tong Amy Hin Yan, Boone Charles, Bussey Howard
Abstract excerpt
BACKGROUND: In S. cerevisiae the beta-1,4-linked N-acetylglucosamine polymer, chitin, is synthesized by a family of 3 specialized but interacting chitin synthases encoded by CHS1, CHS2 and CHS3. Chs2p makes chitin in the primary septum, while Chs3p makes chitin in the lateral cell wall and in the bud neck, and can partially compensate for the lack of Chs2p. Chs3p requires a pathway of Bni4p, Chs4p, Chs5p, Chs6p...
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